Structural Biology Group


The field of structural biology research is concerned with the elucidation of molecular functions through analysis of the three-dimensional architecture of bio-macromolecules, especially proteins and nucleic acids.

In our group we make use of structure determination by X-ray crystallography to determine the structure of proteins at atomic resolution. For functional studies we apply a full range of biophysical methods (UV/vis, fluorescence spectroscopy, SPR, light scattering etc.) to probe protein stability, enzyme activity and receptor-ligand interactions.

Our research is highly interdisciplinary and we tightly network with scientist from other disciplines (biochemistry, biology, chemistry, pharmacy, physics and bioinformatics). We are working in basic research and applied research (e.g. structure based drug design).